GLP-4
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GLP-4™ Metabolic Nasal Spray
The "Gut-Level Protocol" Activator
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The world's first Intranasal Metabolic Stack. Designed to target the 4 Pillars of Human Metabolism (Energy, Insulin, Sirtuins, Lipolysis) without needles, nausea, or muscle loss.
100 Sprays Per Bottle
- Rapid Absorption: Bypasses digestion via Blood-Brain Barrier.
- No Nausea or Muscle Loss: Unlike injections that cause severe side effects.
- Needle-Free: Painless daily metabolic signal.
What is the GLP-4™ Protocol?
GLP-4™ stands for "Gut-Level Protocol" (Gut-Lipid Pathway). It is a non-hormonal, clinical-grade metabolic stack designed to bridge the gap between biological aging and cellular performance.
Why Pills Don't Work (The Bioavailability Problem)
Standard oral NAD+ or NMN supplements are largely destroyed by gastric acids. The Intranasal Advantage: GLP-4™ utilizes a proprietary delivery system to bypass the digestive tract entirely. By delivering the active complex to the vascular-rich nasal mucosa, the ingredients can cross the Blood-Brain Barrier directly, delivering immediate cognitive clarity.
How NAD+ and NMN Support Healthy Weight Loss
NAD+ (Nicotinamide Adenine Dinucleotide) and NMN (Nicotinamide Mononucleotide) are critical coenzymes that power every cell in your body. As we age, NAD+ levels decline by up to 50%, causing metabolism to slow dramatically.
By restoring NAD+ levels through intranasal NMN delivery, GLP-4™ helps:
- Increase cellular energy production — Your mitochondria burn more calories at rest
- Activate sirtuins (SIRT-1) — The "longevity genes" that mimic fasting and improve fat burning
- Improve insulin sensitivity — Glucose is shuttled to muscles, not stored as fat
- Preserve lean muscle mass — Unlike GLP-1 injections that cause muscle wasting
- Zero nausea or digestive issues — No stomach upset, vomiting, or loss of appetite
This is metabolic optimization without the brutal side effects of appetite-suppressing injections.
The 4 Mechanisms of Action
We call it "GLP-4" because it targets the four essential pillars required for metabolic efficiency.
The Furnace
Mitochondrial Biogenesis: Restores youthful NAD+ levels, forcing your mitochondria to produce more ATP energy (Basal Metabolic Rate).
The Switch
Sirtuin Activation: NMN activates "Skinny Genes" (SIRT-1). It mimics the metabolic signaling of fasting, flipping your body's switch into repair-and-burn mode.
The Sensitivity
Insulin Optimization: Improves how your body handles glucose, shuttling carbohydrates into muscle tissue for fuel rather than belly fat.
The Mobilizer
Lipolysis Support: Supports the enzymatic breakdown of triglycerides (lipolysis), ensuring released fat is oxidized effectively.
Currently on Injections? You need this.
If you are taking GLP-1 agonists (Semaglutide/Tirzepatide), you are likely experiencing "The Ozempic Gap"—the massive drop in energy and muscle tone caused by rapid weight loss.
Combat "Ozempic Face"
NAD+ is critical for DNA repair and skin elasticity. GLP-4™ helps maintain cellular health while you lose weight rapidly.
Stop the Fatigue
Injections can leave you feeling drained. GLP-4™ restores the ATP energy production required to feel vibrant and active.
Clinical Validation
Human Trial Confirms Insulin Sensitivity
A clinical trial demonstrated that NMN supplementation significantly increased insulin sensitivity in skeletal muscle of prediabetic women, validating the mechanism of glucose disposal.
The GLP-1 Connection
Why do we call it the Gut-Level Protocol? Research confirms that activating SIRT1 (via NMN) positively regulates the secretion of natural GLP-1 in the gut. You aren't injecting a hormone; you are supporting the machinery that produces it.
Reversing Metabolic Aging
Harvard research demonstrated that declining NAD+ levels are the primary cause of mitochondrial dysfunction. Restoring NAD+ levels was shown to reverse this "energy block," restoring youthful metabolic function.
Clinical Transparency
NAD+ (Nicotinamide Adenine Dinucleotide): The essential coenzyme for cellular energy.
Delivery Agent: Saline solution optimized for nasal mucosal absorption.
Week 1: Begin with 1 spray in each nostril, first thing in the morning on an empty stomach.
Week 2-3: Increase to 2 sprays in each nostril if well-tolerated.
Week 4+: Advance to the full therapeutic dose of 3 sprays in each nostril for maximum metabolic support.
Pro Tip: Take 15-30 minutes before your first meal to maximize the "fasting mimicry" effect and optimize absorption.