Energy
NAD+
The primary electron carrier in cellular respiration. It drives sustained output instead of stimulant spikes.
Cellular metabolism literature
Curetonix · GLP-4
Ozempic making you tired?
GLP-4 · NAD+ and NMN, 10mg each per spray · nasal or sublingual
The shot works. It also leaves a lot of people running on empty, tired, foggy, flat, because aggressive appetite suppression means you're fueling your cells on far less. GLP-4 delivers pharmaceutical-grade NAD+ and NMN, the coenzymes your cells burn for energy. No needles. No nausea. Just the fuel the shot forgot.
NAD+ and NMN, 10mg each
Nasal or sublingual
No needles, no nausea
The Fatigue · 01
Fatigue is one of the most reported side effects of GLP-1 shots.
1 in 20+ report fatigue
Tiredness shows up consistently in GLP-1 side effect reporting, and the reason is simple. When you slash intake hard and fast, you slash the fuel your cells convert into energy at the same time. The scale moves. So does your baseline energy, and often not in the direction anyone wants.
Fatigue is a commonly listed side effect in GLP-1 agonist prescribing information and post-market reporting. This describes the drug class, not GLP-4.
The drug handles appetite. It does nothing for the energy machinery underneath. That's the gap GLP-4 is built to fill, the fuel, not the appetite.
The Link · 02
Why cutting calories that hard can flatten your energy.
Your cells turn fuel into usable energy through NAD+, the coenzyme at the center of cellular respiration. Eat far less and the raw material for that process drops. NAD+ also falls on its own with age. Less fuel plus a falling coenzyme is why "I'm losing weight but I feel wiped" is such a common story.
GLP-1 cuts intake hard
Appetite suppressed, fuel in drops
→
Energy machinery starved
Less substrate for cellular energy
→
NAD+ restores the fuel cycle
The coenzyme your cells run on, delivered directly
The Scope · 03
One coenzyme sits under all four pillars of metabolism.
Delivery
0needles
Transmucosal absorption through nasal or sublingual routes, bypassing first-pass metabolism entirely.
GLP-4 formulation
Per bottle
2,000mg
NAD+ and NMN at 10mg each per spray, 20mg total, 100 sprays per bottle. No fillers, no stimulants.
GLP-4 label
The Product · 04
10mL · 100 sprays · NAD+ + NMN
The Answer · Pharmaceutical-grade NAD+
The metabolic advantage of the shot, without the needle.
GLP-1 agonists work on appetite. GLP-4 works on the machinery underneath: NAD+ and its precursor NMN, the coenzyme system your cells depend on to convert fuel into energy, handle glucose, and mobilize stored fat.
Delivered nasally or sublingually so it absorbs straight through the tissue, bypassing digestion. 10mg per spray, 100 sprays a bottle. No injections, no nausea, no muscle-loss protocol.
Actives
NAD+ + NMN 10mg ea
Format
Nasal or sublingual
Bottle
100 sprays · 10mL
Route
Transmucosal
Get GLP-4
Put the energy back while the shot does its job.
Choose your format, then your supply. The 3-bottle set is Buy 2 Get 1 Free and the better cost per bottle.
GLP-4 · NAD+ + NMN, 10mg each / spray
- Pharmaceutical-grade NAD+ and NMN, no fillers
- Nasal or sublingual, equivalent bioavailability
- 90-day money-back guarantee
90-day guarantee. Run the protocol for three months. If your energy hasn't changed the way you hoped, email us and we refund you.
The Mechanism · 05
What NAD+ actually does.
To be plain: GLP-4 is not a weight-loss drug and it doesn't replace your prescription. It's metabolic support. NAD+ is the coenzyme that carries electrons through cellular respiration, the step that turns fuel into usable energy, and NMN is the precursor your body converts into more of it. Restore both and the energy cycle the shot never touched gets resourced again.
On the shot alone
Appetite down, energy machinery starved of fuel.
With GLP-4
NAD+ restored, the fuel cycle has what it needs to run.
Pathway 1 · Energy
Mitochondrial output
NAD+ is the primary electron carrier in cellular respiration, driving sustained output rather than stimulant peaks.
Pathway 2 · Insulin
Glucose regulation
NAD+ supports insulin signaling and glucose handling, the post-meal dynamics behind energy crashes.
Pathway 3 · Sirtuins
Longevity genes
Sirtuins are NAD-dependent enzymes. Without NAD+ they can't fire, the same pathway caloric restriction activates.
Pathway 4 · Lipolysis
Fat mobilization
NAD+ supports the machinery that releases stored fatty acids for energy.
NAD+'s roles in cellular respiration, sirtuin activation, and metabolism are documented in the biochemistry literature. GLP-1 fatigue is a listed side effect of that drug class. These are separate bodies of research about the drug and the coenzyme. GLP-4 is metabolic support, not a pharmaceutical substitute, and is not claimed to treat, cure, or replace any medication.
Why the set · 06
Three bottles. Because a protocol is a habit, not a hit.
One bottle tells you how you respond. The 3-bottle set runs the protocol long enough for the difference to settle in, at the better price per bottle.
01
A real run, not a sample
Each bottle is 100 sprays. The set carries you through a full protocol window instead of leaving you to reorder mid-stride.
100 sprays per bottle.
02
The third bottle is free
Buy two, the third is on us. $119.98 for three, about $39.99 a bottle versus $59.99 one at a time.
Buy 2 Get 1 Free.
03
Two coenzymes, no stimulants
Pharmaceutical-grade NAD+ and its precursor NMN, nothing else. No caffeine crutch, no proprietary blend hiding the dose. The energy is metabolic, not a jitter.
NAD+ + NMN, 10mg each.
04
90 days to decide
Run it for a quarter. If it hasn't earned its place next to your protocol, email us and get your money back.
Money-back guarantee.
90-day money-back guarantee.
How to take it · 07
One spray. Nasal or under the tongue.
Pick your route
Nasal is faster for an acute lift. Sublingual gives more controlled dosing. Both bypass first-pass metabolism.
Daily, with your protocol
Use it alongside your existing routine. Consistency is what keeps the fuel cycle resourced day to day.
No stimulant timing
It's not caffeine, so there's no late-day cutoff. Take it when it fits your schedule.
Keep meds separate
GLP-4 is support, not a replacement. Keep taking anything your doctor prescribed and check with them before changing a protocol.
The Formula · 08
One active. A clear reason for it.
GLP-4 pairs two compounds that work the same pathway: NAD+ and the precursor your body builds it from, NMN. No B-vitamin filler to fake an energy label, no stimulant to manufacture a spike. The coenzyme your cells run on, plus the raw material to make more of it, at a real dose.
NAD+ & NMN
Two actives · 10mg each / spray
NAD+ is the coenzyme at the center of cellular metabolism. It carries the electrons that drive cellular respiration, supports insulin signaling and glucose handling, activates the NAD-dependent sirtuin enzymes tied to longevity, and supports the fat-mobilization cascade. NMN (nicotinamide mononucleotide) is the direct precursor your body converts into NAD+, so pairing them supplies the coenzyme and the raw material to sustain it. We deliver pharmaceutical-grade NAD+ and NMN at 10mg each per spray, 20mg total, 2,000mg per bottle, intranasally or sublingually so they absorb through the tissue rather than being degraded in digestion.
Research context: NAD+'s central role in cellular respiration, sirtuin activation, glucose metabolism, and lipolysis is well characterized in the biochemistry literature, as is its decline with age. Fatigue is a documented side effect of the GLP-1 agonist drug class. These describe the coenzymes and the drug, not GLP-4. We keep the formula to NAD+ and NMN so the doses are legible and the reason for them is plain.
Third-party tested. We'll always show you exactly what's inside.
Questions · 09
Answered plainly.
Is this a replacement for Ozempic?+
No, and we won't pretend otherwise. GLP-4 is not a GLP-1 drug and doesn't replace a prescription. It's metabolic support built around NAD+ and NMN, the coenzyme system your cells use for energy, aimed at the fatigue side of aggressive calorie reduction. Keep taking what your doctor prescribed.
Why do GLP-1 shots make people tired?+
When intake drops hard and fast, so does the fuel your cells convert into energy. Fatigue is a commonly reported side effect of the drug class for exactly that reason. GLP-4 targets the energy machinery the shot doesn't touch.
Nasal or sublingual, which should I pick?+
Both deliver equivalent bioavailability and both bypass first-pass metabolism. Nasal is faster for an acute lift. Sublingual allows more controlled dosing. Pick whichever fits your routine.
Any nausea or muscle loss?+
None. NAD+ supports metabolic pathways through a mechanism that doesn't produce the nausea, vomiting, or muscle catabolism associated with aggressive calorie-restriction protocols.
What exactly is in it?+
Two actives: pharmaceutical-grade NAD+ and NMN at 10mg each per spray, 20mg total, 100 sprays per bottle, 2,000mg total. No fillers, no stimulants, no proprietary blends.
How does the Buy 2 Get 1 work?+
Add three bottles and the third comes free at checkout, $119.98 for three, about $39.99 a bottle. Same 90-day money-back guarantee.
Buy 2 Get 1 · 90-day guarantee
The shot cut your appetite. Get your energy back.
Pharmaceutical-grade NAD+ and NMN, the coenzymes your cells run on, delivered without needles or nausea. One spray a day, nasal or sublingual, with 90 days to decide it's worth keeping.
Get GLP-4 — Buy 2 Get 190-day money-back guarantee · NAD+ and NMN